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Scientific Papers

Our peer-reviewed research papers in leading scientific journals

2025
Title Authors Journal
The complex phenotype and function of spinal cord microglia during ALS progression and the impact of metabotropic glutamate receptor type 5 down-regulation in SOD1G93A mice Balbi, M., Torazza, C., Altosole, T., Ravera, S., Farinini, E., Tessitore, S., Bacchetti, F., Rosso, F., Musante, I., Alfei, S., Cerminara, M., Puliti, A., Filaci, G., Fenoglio, D., Leardi, R., Fedele, E., Bonanno, G., Milanese, M., Bonifacino, T. Neurobiology of Disease
Chemometric Optimization of Cemented Paste Backfill solutions, Ascensão, G., Farinini, E., Paiva, H.,Ferreira, V.M., Leardi, R. CEES - Construction, Energy, Environment and Sustainability
2024
Title Authors Journal
Blue CdSe/CdS core/crown nanoplatelet light-emitting diodes obtained via a design-of-experiments approach Cirignano, M., Roshan, H., Farinini, E., Di Giacomo, A., Fiorito, S., Piccinotti, D., Khabbazabkenar, S., Di Stasio, F., Moreels, I. Nanoscale
Development of Eco-efficient Limestone Calcined Clay Cement (LC3) Mortars by a Multi-step Experimental Design Ascensão, G., Farinini, E., Ferreira, V.M., Leardi, R. Chemometrics and Intelligent Laboratory Systems
Chestnut Episperm as a Promising Natural Source of Phenolics from Agri-Food Processing by-Products: Optimisation of a Sustainable Extraction Protocol by Ultrasounds Donno, D., Turrini, F., Farinini E., Mellano M.G., Boggia R., Beccaro G.L., Gamba G. Agriculture
2023
Title Authors Journal
Two photons are better than one: continuous flow synthesis of β-lactones through a doubly photochemically-activated Paternò Büchi reaction Minuto, F., Farinini, E., Leardi, R., Solokha, P., Basso, A. Journal of Flow Chemistry
Tailoring Water-based Graphite Conductive Ink Formulation for Enzyme Stencil-Printing: Experimental Design to Enhance Wearable Biosensors Performance Marchianò, V., Tricase, A., Caputo, M., Farinini, E., Leardi, R., Imbriano, A., Leech, D., Kidayaveettil, R., Gentile, L., Torsi, L., Macchia, E., Bollella, P. Chemistry of Materials
Supervised classification combined with genetic algorithm variable selection for a fast identification of polymeric microdebris using infrared reflectance Ferreiro, B., Farinini, E., Leardi, R., Andrade, J. Marine Pollution Bulletin
PLX4032 resistance of patient-derived melanoma cells: crucial role of oxidative metabolism Garbarino, O., Valenti, G. E., Monteleone L., Pietra, G., Mingari, M. C., Benzi, A., Santina Bruzzone, S., Ravera, S., L., Leardi, R., Farinini E., Vernazza, S., Grottoli, M., Marengo, B., Domenicotti, C. Frontiers in Oncology
Intra-source provenance study on Monte Arci (Sardinia) obsidian by pXRF: Role of the data acquisition and analysis tools Mameli, V., Sanna Angotzi, M., Farinini, E., Leardi, R., Lugliè, C., Cannas, C. Heliyon
Experimental Design approach applied to the removal of personal care products from urban wastewater through γ-cyclodextrin polymers Forni, F., Farinini, E., Leardi, R., Rinaldo, A. Journal of Environmental Management
2022
Title Authors Journal
Multi-Elemental Analysis as a Tool to Ascertain the Safety and the Origin of Beehive Products: Development, Validation, and Application of an ICP-MS Method on Four Unifloral Honeys Produced in Sardinia, Italy Mara, A., Deidda, S., Caredda, M., Ciulu, M., Deroma, M., Farinini, E., Floris, I., Langasco, I., Leardi, R., Pilo, M.I., Spano, N., Sanna, G. Molecules
A Preliminary Color Study of Different Basil-Based Semi-Finished Products during Their Storage Turrini, F., Farinini, E., Leardi, R., Grasso, F., Orlandi, V., Boggia, R. Molecules
From electromagnetic to sediment textural maps: an integrated approach to unravel the intra-point-bar variability of sediment properties Bellizia, E., Tognin, D., Boaga, J., Cassiani, G., Leardi, R., Finotello, A., D'Alpaos, A., Ghinassi, M. Journal of the Geological Society
2021
Title Authors Journal
Potential Role of miRNAs in the Acquisition of Chemoresistance in Neuroblastoma Marengo, B., Pulliero, A., Corrias, M. V., Leardi, R., Farinini, E., Fronza, G., Domenicotti, C. Journal of Personalized Medicine
Effects of visual training on motor performance in young tennis players using FitLight Trainer Forni, F., Farinini, E., Leardi, R., Rinaldo, A. Journal of Sports Medicine and Physical Fitness
PKCα Inhibition as a Strategy to Sensitize Neuroblastoma Stem Cells to Etoposide by Stimulating Ferroptosis Monteleone, L., Speciale, A., Valenti, G. E., Leardi, R., Farinini, E., Traverso, N., Ravera, S., Garbarino, O., Domenicotti, C. Antioxidants
Background, applications and issues of the experimental designs for mixture in the food sector Squeo, G., De Angelis, D., Leardi, R., Summo, C., Caponio, F. Foods
2020
Title Authors Journal
Electrochemical preconcentration coupled with spectroscopic techniques for trace lead analysis in olive oils Baldo, M.A., Stortini, A.M., Oliveri, P., Leardi, R., Moretto, L.M., Ugo, P. Talanta
Effect of the irrigation method and genotype on the bioaccumulation of toxic and trace elements in rice Spanu, A., Valente, M., Langasco, I., Leardi, R., Orlandoni, A.M., Ciulu, M., Deroma, M.A., Spano, N., Barracu, F., Pilo, M.I., Sanna, G. Science of The Total Environment
Chemometric challenges in development of paper-based analytical devices: Optimization and image processing Hamedpour, V., Oliveri, P., Leardi, R., Citterio, D. Analytica Chimica Acta
2019
Title Authors Journal
Assessing the influence of pH and cationic strength on i-motif DNA structure Iaccarino, N., Di Porzio, A., Amato, J., Pagano, B., Brancaccio, D., Novellino, E., Leardi, R., Randazzo, A. Analytical and Bioanalytical Chemistry
An innovative green extraction and re-use strategy to valorize food supplement by-products: Castanea sativa bud preparations as case study Turrini, F., Donno, D., Boggia, R., Beccaro, G. L., Zunin, P., Leardi, R., Pittaluga, A. M. Food Research International
2018
Title Authors Journal
Optimization of the Ultrasonic-Assisted Extraction of Phenolic Compounds from Oryza Sativa L.'Violet Nori'and Determination of the Antioxidant Properties of its Caryopses and Leaves Turrini, F., Boggia, R., Leardi, R., Borriello, M., Zunin, P. Molecules
Multivariate evaluation of the effect of the particle size distribution of an Active Pharmaceutical Ingredient on the performance of a pharmaceutical drug product: a real-case study Copelli, D., Cavecchi, A., Merusi, C., Leardi, R. Chemometrics and Intelligent Laboratory Systems
Sequential "asymmetric" D-optimal designs: a practical solution in case of limited resources and not equally expensive experiments Copelli, D., Falchi, A., Ghiselli, M., Lutero, E., Osello, R., Riolo, D., Schiaretti, F., Leardi, R. Chemometrics and Intelligent Laboratory Systems
Fabrication of paper-based analytical devices optimized by central composite design Hamedpour, V., Leardi, R., Suzuki, K., Citterio, D. Analyst
Design of Experiment as a powerful tool when applying Finite Element Method: a case study on prediction of hot rolling process parameters Bordonaro, G.G., Leardi, R., Diviani, L., Berto, F. Frattura ed Integrità Strutturale
D-Optimal designs Leardi, R. Encyclopedia of Analytical Chemistry
2017
Title Authors Journal
Building of prediction models by using Mid-Infrared spectroscopy and fatty acid profile to discriminate the geographical origin of sheep milk Caredda, M., Addis, M., Ibba, I., Leardi, R., Scintu, M.F., Piredda, G., Sanna, G. LWT - Food Science and Technology
Olive fruits and vacuum impregnation, an interesting combination for dietetic iron enrichment Zunin, P., Turrini, F., Leardi, R., Boggia, R. Journal of Food Science and Technology
Data Handling Leardi, R. In "Advances in Food Diagnostics, Second Edition", Wiley - Blackwell
Tools based on multivariate statistical analysis for classification of soil and groundwater in Apulian agricultural sites Ielpo, P., Leardi, R., Pappagallo, G., Uricchio, V.F. Environmental Science and Pollution Research
2016
Title Authors Journal
Prediction of fatty acid content in sheep milk by Mid-Infrared spectrometry with a selection of wavelengths by Genetic Algorithms Caredda, M., Addis, M., Ibba, I., Leardi, R., Scintu, M.F., Piredda, G., Sanna, G. LWT - Food Science and Technology
Spectroscopic fingerprinting techniques for food characterisation Casale, M., Bagnasco, L., Casolino, C., Lanteri, S., Leardi, R. Acta Imeko
A Biosurfactant/Polystyrene Polymer Partition System for Remediating Coal Tar-Contaminated Sediment Wilton, N.M., Zeigler, C.D., Leardi, R., Robbat Jr., A. Soil and Sediment Contamination: An International Journal
UV-VIS spectroscopy for monitoring yogurt stability during storage time Aliakbarian, B., Bagnasco, L., Perego, P., Leardi, R., Casale, M. Analytical Methods
Actuator Performance Comparison by an Integrated Multivariate Approach Copelli, D., Bodria, A., Magnani, I., Militerno, G., Ponticelli, M., Usberti, F., Leardi, R. Pharmaceutica Analytica Acta
Oxysterol mixture and, in particular, 27-hydroxycholesterol drive M2 polarization of human macrophages Marengo, B., Bellora, F., Ricciarelli, R., De Ciucis, C., Furfaro, A., Leardi, R., Colla, R., Pacini, D., Traverso, N., Moretta, A., Pronzato, M.A., Bottino, C., Domenicotti, C. Biofactors
2015
Title Authors Journal
Determination and speciation of trace and ultratrace selenium ions by energy-dispersive X-ray fluorescence spectrometry using graphene as solid adsorbent in dispersive micro-solid phase extraction Kocot, K., Leardi, R., Walczak, B., Sitko, R. Talanta
Total and "free" lipids in commercial infant formulas: fatty acid composition and their stability to oxidation Zunin, P., Boggia, R., Turrini, F., Leardi, R. Food Chemistry
Chemometric approach to open validation protocols: Prediction of validation parameters in multi-residue ultra-high performance liquid chromatography-tandem mass spectrometry methods Alladio, E., Pirro, V., Salomone, A., Vincenti, M., Leardi, R. Analytica Chimica Acta
Ultra-trace measurement of Dechloranes to investigate food as a route of human exposure L'Homme, B., Calaprice, C., Calvano, C.D., Zambonin, C., Leardi, R., Focant, J.F. Chemosphere
Fingerprint detection and process prediction by multivariate analysis of fed-batch monoclonal antibody cell culture data Sokolov, M., Soos, M., Neunstoecklin, B., Morbidelli, M., Butté, A., Leardi, R., Solacroup, T., Stettler, M., Broly, H. Biotechnology Progress
2014
Title Authors Journal
Experimental design in analytical chemistry – Part I: Theory Ebrahimi-Najafabadi, H., Leardi, R., Jalali-Heravi, M. Journal of AOAC INTERNATIONAL
Experimental design in analytical chemistry – Part II: Applications Ebrahimi-Najafabadi, H., Leardi, R., Jalali-Heravi, M. Journal of AOAC INTERNATIONAL
Direct GC–(EI)MS determination of fatty acid alkyl esters in olive oils Boggia, R., Borgogni, C., Hysenaj, V., Leardi, R., Zunin, P. Talanta
Application of genetic algorithms for pixel selection in multivariate image analysis for a QSAR study of trypanocidal activity for quinone compounds and design new quinone compounds Niazi, A., Sarkhosha, M., Khorshidi, N., Leardi, R. Chemometrics and Intelligent Laboratory Systems
2013
Title Authors Journal
Solving the sign indeterminacy for multiway Models Bro, R., Leardi, R., Giørtz Johnsen, L. Journal of Chemometrics
Application of a GA–PLS strategy for variable reduction of electronic tongue signals Prieto, N., Oliveri, P., Leardi, R., Gay, M., Apetrei, C., Rodriguez-Méndez, M.L., de Saja, J.A. Sensors and Actuators B: Chemical
Dehydration of PDO Genovese basil leaves (Ocimum basilicum maximum L. cv Genovese Gigante) by direct osmosis Boggia, R., Leardi, R., Zunin, P., Bottino, A., Capannelli, G. Journal of Food Processing and Preservation
2012
Title Authors Journal
A multiway chemometric and kinetic study for evaluating the thermal stability of edible oils by 1H NMR analysis: Comparison of methods Cordella, C.B.Y., Tekye, T., Rutledge, D.N., Leardi, R. Talanta
Application of Multi-way Analysis to UV-Visible Spectroscopy, Gas Chromatography and Electronic Nose Data for Wine Ageing Evaluation Prieto, N., Rodriguez-Méndez, M.L., Leardi, R., Oliveri, P., Hernando-Esquisabel, D., Iñiguez-Crespo, M., de Saja, J.A. Analytica Chimica Acta
Genetic Algorithms in Chemistry Niazi, A., Leardi, R. Journal of Chemometrics
Prediction of the optimum harvest time of 'Scarlet' apples using DR-UV–Vis and NIR spectroscopy Bertone, E., Venturello, A., Leardi, R., Geobaldo, F. Postharvest Biology and Technology
Detection of addition of barley to coffee using near infrared spectroscopy and chemometric techniques Ebrahimi-Najafabadi, H., Leardi, R., Oliveri, P., Casolino, M.C., Jalali-Heravi, M., Lanteri, S. Talanta
2011
Title Authors Journal
Three-way Principal Component Analysis applied to Noodles Sensory Data Analysis Cordella, C.B.Y., Leardi, R., Rutledge, D. Chemometrics and Intelligent Laboratory Systems
Effect of the Addition of Membrane Processed Olive Mill Waste Water (OMWW) to Extra Virgin Olive Oil Zunin, P., Fusella, G.C., Leardi, R., Boggia, R., Bottino, A., Capannelli, G. Journal of the American Oil Chemists' Society
2010
Title Authors Journal
Oxidative stability of virgin olive oil enriched with carnosic acid Zunin, P., Leardi, R., Boggia, A., Bisio, G., Romussi, G. Food Research International
Energy savings using on-line mltivariate distillation monitoring MacNamara, K., Leardi, R., Interwies, U. In "Distilled Spirits: New Horizons – Energy, Environmental and Enlightment"
2009
Title Authors Journal
Experimental design in chemistry: a tutorial Leardi, R. Analytica Chimica Acta
Application of HSSE-GC-MS and chemometric methods to the quantification of pine nuts and Pecorino in 'Pesto Genovese' Zunin, P., Leardi, R., Boggia, R. The Journal of AOAC International
Annual and spatial variations of chemical and physical properties in the Ross Sea surface waters (Antarctica) Massolo, S., Messa, R., Rivaro, P., Leardi, R. Continental Shelf Research
Principal component analysis of colour measurements of patinas and coating systems for outdoor bronze monuments Luciano, G., Leardi, R., Letardi, P. Journal of Cultural Heritage
Multivariate calibration of mango firmness using vis/NIR spectroscopy and acoustic impulse method Valente, M., Leardi, R., Self, G., Luciano, G., Pain, J.P. Journal of Food Engineering
2008
Title Authors Journal
Classification of GC-MS measurements of wines by combining a novel strategy for data dimension reduction and variable selection techniques Ballabio, D., Skov, T., Leardi, R., Bro, R. Journal of Chemometrics
Poloxamer 407 as a Solubilising Agent for Tolfenamic Acid and as a Base for a Gel Formulation Cafaggi, S., Russo, E., Caviglioli, G., Parodi, B., Stefani, R., Sillo, G., Leardi, R., Bignardi, G. European Journal of Pharmaceutical Sciences
2007
Title Authors Journal
A composite sensor array impedentiometric electronic tongue - Part II Discrimination of basic tastes Pioggia, G., Di Francesco, F., Marchetti, A., Ferro, M., Leardi, R., Ahluwalia, A. Biosensors and Bioelectronics
Simultaneous kinetic-spectrophotometric determination of sulfide and sulfite by partial least squares and genetic algorithm variable selection Ghasemi, J., Ebrahimi, D.M., Hejazi, L., Leardi, R., Niazi, A. Journal of Analytical Chemistry
Genetic algorithms in chemistry Leardi, R. Journal of Chromatography A
Preparation and evaluation of nanoparticles made of chitosan or n-trimethyl chitosan and a cisplatin-alginate complex Cafaggi, S., Russo, E., Stefani, R., Leardi, R., Caviglioli, G., Parodi, B., Bignardi, G., Viale, M., De Totero, D. Journal of Controlled Release
Optimisation of a glucose biosensor setup based on a Ni/Al HT matrix Mignani, A., Luciano, G., Lanteri, S., Leardi, R., Scavetta, E., Tonelli, D. Analitica Chimica Acta
A comparative study between PLS and OSC-PLS in the simultaneous determination of lead and mercury in water samples: effect of wavelength selection Niazi, A., Azizi, A., Leardi, R. Canadian Journal of Analytical Sciences and Spectroscopy
2006
Title Authors Journal
Industrial experiences with Multivariate Statistical Analysis of batch process data Chang, L., Leardi, R., Pell, R.J., Seasholtz, M.B. Chemometrics and Intelligent Laboratory Systems
Untersuchung von Apfelsäften mit Hilfe der mittleren Infrarotspektroskopie Patz, C.D., Dietrich, H., Leardi, R. Deutsche Lebensmittel-Rundschau
Characterizing the pollution produced by an industrial area. Chemometric methods applied to the Lagoon of Venice Carrer, S., Leardi, R. Science of the Total Environment
2005
Title Authors Journal
Fast GC Analysis of Major Volatile Compounds in Distilled Alcoholic Beverages. Optimisation of Injection and Chromatographic Conditions MacNamara, K., Leardi, R., Sabuneti, A. Analytica Chimica Acta
Preparation and evaluation of a chitosan salt-poloxamer 407 based matrix for buccal drug delivery Cafaggi, S., Leardi, R., Parodi, B., Caviglioli, G., Russo, E., Bignardi, G. Journal of Controlled Release
2004
Title Authors Journal
Sequential application of backward interval PLS and Genetic Algorithms for the selection of relevant spectral regions Leardi, R., Nørgaard, L. Journal of Chemometrics
Direct thermal extraction and gas chromatography
Direct thermal extraction and gas chromatography-mass spectrometry analysis of volatile compounds of extra-virgin olive oils Zunin, P., Boggia, R., Lanteri, S., Leardi, R., De Andreis, R., Evangelisti, F. Journal of Chromatography A
Developments in 2-Dimensional Gas Chromatography with Heart-Cutting MacNamara, K., Leardi, R., Hoffmann, A. LC-GC North America
Polycyclic Aromatic Hydrocarbons (PAHs) Assessment in the Sediments of the Porto Torres Harbour (Northern Sardinia, Italy) De Luca, G., Furesi, A., Leardi, R., Micera, G., Panzanelli, A., Piu, P.C., Sanna, G. Marine Chemistry
2003
Title Authors Journal
Selection of near infrared wavelengths using genetic algorithms for the determination of seed moisture content Lestander, T.A., Leardi, R., Geladi, P. Journal of Near Infrared Spectroscopy
Developments in 2-Dimensional Gas Chromatography with Heart-Cutting MacNamara, K., Leardi, R., Hoffmann, A. LC-GC Europe
Application of three-way principal component analysis to the evaluation of two-dimensional maps in proteomics Marengo, E., Leardi, R., Robotti, E., Righetti, P.G., Antonucci, F., Cecconi, D. Journal of Proteome Research
Selection of internal standards in inductively coupled plasma atomic emission spectrometry by Principal Component Analysis Grotti, M., Leardi, R., Frache, R. Journal of Analytical Atomic Spectroscopy
Genetic-algorithm-based wavelength selection in multicomponent spectrophotometric determination by PLS: application on copper and zinc mixture Ghasemi, J., Niazi, A., Leardi, R. Talanta
An Example of Application of a Mixture Design with constraints to a Pharmaceutical Formulation Cafaggi, S., Leardi, R., Parodi, B., Caviglioli, G., Bignardi, G. Chemometrics and Intelligent Laboratory Systems
2002
Title Authors Journal
Combined effects of inorganic acids in inductively coupled plasma optical emission spectrometry Grotti, M., Leardi, R., Frache, R. Spectrochimica Acta, Part B
Chemometrics: from classical to Genetic Algorithms Leardi, R. Grasas y Aceites
Variable selection for multivariate calibration using a Genetic Algorithm: Prediction of additive concentrations in polymer films from FTIR spectral data Leardi, R., Seasholtz, M.B., Pell, R.J. Analytica Chimica Acta
Genetic Algorithms in Feature Selection Leardi, R. NAmICS newsletter
2001
Title Authors Journal
Feature selection by genetic algorithms for mass spectral classifiers Yoshida, H., Leardi, R., Funatsu, K., Varmuza, K. Analytica Chimica Acta
Quantifying main trends in lysozyme nucleation: The effect of precipitant concentration, supersaturation and impurities Burke, M.W., Leardi, R., Judge, R.A., Pusey, M.L. Crystal Growth & Design
Genetic Algorithms in Chemometrics and Chemistry: a review Leardi, R. Journal of Chemometrics
2000
Title Authors Journal
Application of genetic algorithm-PLS for feature selection in spectral data sets Leardi, R. Journal of Chemometrics
Three-Mode Principal Component Analysis of monitoring data from Venice lagoon Leardi, R., Armanino, C., Lanteri, S., Alberotanza, L. Journal of Chemometrics
Application of the Principal Component Analysis (PCA) to the ecological study of an artificial environment: the tunny-fishing net of Camogli (Ligurian Sea) Mariottini, G.L., Leardi, R., Carli, A. Journal of Biological Research - Boll. Soc. It. Biol. Sper.
Inorganic Pollution in the Soil of an Industrial Plant. A Chemometric Study Crisponi, G., Cristiani, F., Leardi, R., Nurchi, V.M. Annali di Chimica
Monitoring of heavy metals and butyltin compounds in coastal waters of Ligurian Sea: Results of a mussel watch project Rivaro, P., Abelmoschi, M.L., Leardi, R., Frache, R. Toxicological & Environmental Chemistry
1999
Title Authors Journal
Direct Injection of Distilled Spirits with PTV Matrix Removal: The Perfect Splitless Injection? MacNamara, K., Leardi, R., Hoffmann, A. G.I.T. Laboratory Journal
Three-Way Principal Component Analysis as a Powerful Tool to Process Marine Environmental Data Sets Grotti, M., Rivaro, P., Leardi, R., Magi, E. Annali di Chimica
Determination of Mn by Graphite Furnace Atomic Absorption Spectrometry: matrix effect control by multiple linear regression model Grotti, M., Leardi, R., Gnecco, C., Frache, R. Spectrochimica Acta, part B
1998
Title Authors Journal
Extraction of representative subsets by potential function method and genetic algorithms Pizarro Millán, C., Forina, M., Casolino, C., Leardi, R. Chemometrics and Intelligent Laboratory Systems
Genetic Algorithms applied to feature selection in PLS regression: how and when to use them Leardi, R., Lupiáñez González, A. Chemometrics and Intelligent Laboratory Systems
Empirical modelling of interferences in electrothermal atomization atomic absorption spectrometry Grotti, M., Leardi, R., Frache, R. Analytica Chimica Acta
1997
Title Authors Journal
Seasonal variations in levels of butyltin compounds in mussel tissues sampled in a oil port Rivaro, P., Frache, R., Leardi, R. Chemosphere
Optimisation of the isocratic separation of dithranol and related compunds by Reversed Phase Liquid Chromatography Fernandes de Aguiar, P., Vander Heyden, Y., Massart, D.L., Leardi, R., de Beer, J.O. Acta Chromatographica
Influence of Heat-Treatment on the Volatile Compounds of Milk Contarini, G., Povolo, M., Leardi, R., Toppino, P.M. Journal of Agricultural and Food Chemistry
1996
Title Authors Journal
Application of chemometrics to the production of friction materials: analysis of previous data and search for new formulations Drava, G., Leardi, R., Portesani, A., Sales, E. Chemometrics and Intelligent Laboratory Systems
Selection of aroma components to predict sensory quality of Kenyan black teas using genetic algorithms for multiple regression models Aishima, T., Togari, N., Leardi, R. Food Science and Technology International
Development and set-up of drug electroanalysis by experimental design: a survey Gratteri, P., Furlanetto, S., La Porta, E., Pinzauti, S., Leardi, R. Il Farmaco
Multivariate approach to the study of interferences in graphite furnace atomic absorption spectrometry Grotti, M., Magi, E., Leardi, R. Analytica Chimica Acta
Genetic Algorithm as a tool for selection of D-optimal design Broudiscou, A., Leardi, R., Phan-Tan-Luu, R. Chemometrics and Intelligent Laboratory Systems
Lipid supplementation of dairy cows' diet: effects on milk fat composition Contarini, G., Toppino, P.M., Leardi, R., Polidori, F., Savoini, G., Bertocchi, L. Journal of Agricultural and Food Chemistry
1995
Title Authors Journal
Transfer of Calibration Function in Near-Infrared Spectroscopy Forina, M., Drava, G., Armanino, C., Boggia, R., Lanteri, S., Leardi, R., Corti, P., Conti, P., Giangiacomo, R., Galliena, C., Bigoni, R., Quartari, I., Serra, C., Ferri, D., Leoni, O., Lazzeri, L. Chemometrics and Intelligent Laboratory Systems
Design and optimization of variables in the adsorptive stripping voltammetric determination of rufloxacin in tablets, human plasma and urine Furlanetto, S., Gratteri, P., Pinzauti, S., Leardi, R., Dreassi, E., Santoni, G. Journal of Pharmaceutical and Biomedical Analysis
Robust regression and outlier detection for non-linear models using genetic algorithm Vankeerberghen, P., Smeyers-Verbeke, J., Leardi, R., Carr, C.L., Massart, D.L. Chemometrics and Intelligent Laboratory Systems
Genetic Algorithms as a tool for wavelength selection in multivariate calibration Jouan-Rimbaud, D., Massart, D.L., Leardi, R., De Noord, O. Analytical Chemistry
Optimization by Experimental Design of the adsorptive stripping voltammetric parameters in the determination of cinoxacin Gratteri, P., Furlanetto, S., Pinzauti, S., Leardi, R., Corti, P. Electroanalysis
1994
Title Authors Journal
Application of a Genetic Algorithm to feature selection under full validation conditions and to outlier detection Leardi, R. Journal of Chemometrics
Use of Experimental Design to optimize the performances of the volatile compounds extraction by using dynamic headspace technique followed by TCT/GC Contarini, G., Leardi, R. Journal of High Resolution Chromatography
1993
Title Authors Journal
Studio sulla prevalenza di alcune infezioni virali nei tossicodipendenti Masino, M., Carubia, F., Cartasegna, A., Leardi, R., Semino, G., Massacane, R. La Trasfusione del Sangue
A program for non-orthogonal rotation in factor analysis Sarabia, L., Ortiz, M.C., Leardi, R., Drava, G. Trends in Analytical Chemistry
Caratterizzazione di acque minerali italiane mediante tecniche statistiche multivariate Sferlazzo, G., Puggioni, V.R., Franco, M.A., Leardi, R., Piana, A., Azara, A., Castiglia, P. Igiene moderna
Valutazione della genuità del burro mediante analisi di trigliceridi ed acidi grassi Contarini, G., Leardi, R., Pezzi, C., Toppino, P.M. La Rivista Italiana delle Sostanze Grasse
1992
Title Authors Journal
Genetic Algorithms as a strategy for feature selection Leardi, R., Boggia, R., Terrile, M. Journal of Chemometrics
Pianificazione degli esperimenti per il calcolo di una curva di calibrazione Leardi, R., Marengo, E., Todeschini, R., Cozzoli, O., Carrer, G., Contarini, G., Marini, D. La Rivista Italiana delle Sostanze Grasse
1991
Title Authors Journal
Building decision rules by chemometric analysis: application to olive oil Aparicio, R., Ferreiro, L., Leardi, R., Forina, M. Chemometrics and Intelligent Laboratory Systems
A class modelling technique based on potential functions Forina, M., Armanino, C., Leardi, R., Drava, G. Journal of Chemometrics
Multivariate data analysis in classification of musts and wines of the same variety according to vintage year Seeber, R., Sferlazzo, G., Leardi, R., Della Serra, A., Versini, G. Journal of Agricultural and Food Chemistry
Determinazione della retta di calibrazione di un metodo analitico: valutazione del potere predittivo con la tecnica di 'cross-validation' Cozzoli, O., Carrer, G., Contarini, G., Leardi, R., Marengo, E., Marini, D., Todeschini, R., Zambarbieri, G. La Rivista Italiana delle Sostanze Grasse
A new procedure for the visual inspection of multivariate data of different geographic origin Leardi, R., Marengo, E., Todeschini, R. Chemometrics and Intelligent Laboratory Systems
Vases et formes inédites chez Saturninus et Satto Lahanier, Ch., Leardi, R., Leclaire, A., Lutz, M., Malfoy, J.-M. Rei Cretariae Romanae Fautorum acta
1990
Title Authors Journal
Multivariate feature selection and classification in discriminating 3 white wines from Latium Armanino, C., Leardi, R., Drava, G., Piracci, A. Annali di Chimica
Classification and prediction ability of pattern recognition methods applied to sea-water fish Franco, M.A., Seeber, R., Sferlazzo, G., Leardi, R. Analytica Chimica Acta
Precisione dei metodi di prova - Determinazione della ripetibilità e riproducibilità di un metodo analitico chimico-fisico mediante esperimenti interlaboratorio Cozzoli, O., Bernardini, M., Carrer, G., Contarini, G., Leardi, R., Marini, D., Todeschini, R., Zambarbieri, G. La Rivista Italiana delle Sostanze Grasse
1989
Title Authors Journal
Esperimento fattoriale frazionato Bernardini, M., Cozzoli, O., Carrer, G., Contarini, G., Leardi, R., Marini, D., Todeschini, R., Zambarbieri, G. La Rivista Italiana delle Sostanze Grasse
Chemometric analysis of Tuscan olive oils Armanino, C., Leardi, R., Lanteri, S., Modi, G. Chemometrics and Intelligent Laboratory Systems
Differenze nella composizione chimica tra la gelatina reale monoflora e la gelatina reale multiflora Leardi, R., Cipro, G. Rivista della Società Italiana di Scienza dell'Alimentazione
1988
Title Authors Journal
PARVUS - MS-DOS: a package for general pattern recognition Forina, M., Leardi, R. Trends in Analytical Chemistry
PARVUS: an extendable package of programs for data exploration, classification and correlation Forina, M., Leardi, R., Armanino, C., Lanteri, S. Elsevier Scientific Software
Methods of Varimax rotation in factor analysis with applications in clinical and food chemistry Forina, M., Armanino, C., Lanteri, S., Leardi, R. Journal of Chemometrics
1987
Title Authors Journal
Caratterizzazione dell'origine di oli di oliva extravergini mediante metodi chemiometrici applicati alla frazione sterolica Leardi, R., Paganuzzi, V. La Rivista Italiana delle Sostanze Grasse
A program for varimax rotation in factor analysis Forina, M., Lanteri, S., Leardi, R. Trends in Analytical Chemistry
Pattern recognition study of biochemical assays for liver function Armanino, C., Leardi, R., Roda, A., Simoni, P. Analytica Chimica Acta
1986
Title Authors Journal
A routine to change an MS-DOS program during run-time Leardi, R., Forina, M. Trends in Analytical Chemistry
1984
Title Authors Journal
Heterogeneity of presynaptic muscarinic receptors regulating neurotransmitter release in the rat brain Raiteri, M., Leardi, R., Marchi, M. The Journal of Pharmacology and Experimental Therapeutics
Effects of long-term drug treatments on the sensitivity of presynaptic receptors regulating neurotransmitter release Raiteri, M., Pittaluga, A., Leardi, R., Maura, G., Marchi, M. Annali dell'Istituto Superiore di Sanità

Conference Contributions

Our presentations at international conferences and scientific meetings

2024
Title Authors Conference
Functionalized carbon nanomaterials in cement, a multivariate approach Amata, C., Panizzi, S., Farinini, E., Lavagna, L., Pavese, M. European Conference on Composite Materials ECCM21, Nantes (FR)
Optimizing a sustainable approach: green extraction of anthocyanins from Apulian pigmented wheat landraces Coniglio, C., Calvano, C. D., Farinini, E., Cataldi, T.R.I., Patruno, A., Carriglia, M., Longobardi, F. XXVIII Congresso Nazionale della Società Chimica Italiana, Milano (IT)
From batch to flow chemistry: study of an industrial reductive amination reaction Buccioli, M., Farinini, E., Leardi, R., Moro, A., Maes, B., Basso, A. Ischia Advanced School of Organic Chemistry 2024 - IASOC24, Ischia
2023
Title Authors Conference
Development of eco-efficient cements by a multi-step Experimental Design Farinini, E., Leardi, R., Ascensão, G. Colloquium Chemometricum Mediterraneum XI (CCMXI), Padova (IT)
Blue-emitting CdSe/CdS core-crowned nanoplatelets: the power of Design of Experiments on optical performances and LED fabrication Cirignano, M., Roshan, H., Di Giacomo, A., Piccinotti, D., Fiorito, S., Khabbazabkenar, S., Farinini, E., Leardi, R., Prato, M., Di Stasio, F., Moreels, I. 14th International Conference on Optical Probes of Organic and Hybrid Semiconductors (OP2023), Como (IT)
Study of a doubly photochemically activated Paternò-Büchi Reaction through Design of Experiments Minuto, F., Farinini, E., Leardi, R., Solokha, P., Basso, A. XLVII "A. Corbella" International Summer School on Organic Synthesis (ISOS2023), Gargnano (IT)
Development of eco-efficient cements by a multi-step Experimental Design Farinini, E., Leardi, R., Ascensão, G. PhD day, Genova (IT)
2022
Title Authors Conference
Supervised Classification Combined with Genetic Algorithm Variable Selection for Microplastics Measured by Infrared Spectroscopy Ferreiro, B., Andrade, J.M., Leardi, R., Farinini, E. XXVI Encontro Galego-Português de Química, Santiago de Compostela (Spain)
Partial deletion of mGluR5 affects microglia inflammatory phenotype, bioenergetic characteristics, and red-ox state during ALS progression in SOD1G93A mice Balbi, M., Bonifacino, T., Ravera, S., Fenoglio, D., Altosole, T., Filaci G., Leardi, R., Farinini, E., Cerminara, M., Puliti, A., Milanese, M., Bonanno, G. Federation European Neuroscience Society (FENS) Forum Congress, Paris (FR)
NLC synthesis optimization process of lycopene enriched S-CO2 extract Cavagnero, C., Farinini, E., Gueguen, V., Leardi, R., Pavon-Djavid, G., Botto, A., Viscardi, G. First Symposium for YouNg Chemists: Innovation and Sustainability (SYNC2022), Roma (IT)
A chemometric approach for the development of a new cleaning strategy of iron stains on Carrara marbles and its evaluation through image analysis Cardellicchio, F., Farinini, E., Malegori, C., Leardi, R., Salvi, A.M., Oliveri, P. XIX Congresso Nazionale della Divisione di Chimica dell'Ambiente e dei Beni Culturali, Torino
2021
Title Authors Conference
Linking the performance of lithium sulfur batteries to electrode composition and electrolyte formulation through mixture process design of experiments Venezia, E., Ricci, M., Salimi, P., Farinini, E., Zaccaria, R.P. The International Conference on Lithium-Sulfur Batteries (ICLSB)
Characterization of a raw material through analytical profiles and data fusion Farinini, E., Leardi, R. XVIII Chemometrics in Analytical Chemistry (CAC)
Characterization of a raw material through analytical profiles and data fusion Farinini, E., Leardi, R. XXVII Congresso Nazionale della Società Chimica Italiana (SCI)
Product monitoring and exploratory analysis of historical data Farinini, E., Leardi, R. International Conference on NIR (ICNIRS)
Optimization of supercritical CO2 oil extraction from waste of tomatoes paste production Cavagnero, C., Micera, M., Destefano, R., Farinini, E., Botto, A., Leardi, R., Viscardi, G. Merck Young Chemists' Symposium 2021, Rimini (IT)
2019
Title Authors Conference
NIR Spectroscopy as Fast Quality Control Method for Pet Food Leardi, R., Costa, L., Canessa, C., Chiardo, C., Luccardi, A. 10th Colloquium Chemiometricum Mediterraneum, Menorca (Spain)
Approcci analitici non distruttivi e analisi statistica multivariata: l'accoppiata vincente per il settore lattierocaseario Leardi, R., Caredda, M., Malegori, C. Il laboratorio al servizio dell'allevatore: innovazioni e applicazioni, Matera
2018
Title Authors Conference
Optimization of chromatographic methods by experimental design Leardi, R. The 41st Symposium Chromatographic Methods of Investigating Organic Compounds, Szczyrk (Poland)
Multivariate Evaluation of Particle Size Distribution of an Active Pharmaceutical Ingredient Copelli, D., Leardi, R. Food and Drug Testing 2018, Genova
2017
Title Authors Conference
Is a New Sample "compatible" with the Previous Ones? Outlier Detection by T2 and Q Diagnostics Leardi, R. Chemometrics in Forensic Sciences, Torino
Sequential "Asymmetric" D-Optimal Designs: A Practical Solution in Case of Limited Resources and Not Equally Expensive Experiments Copelli, D., Cuoghi, E., Falchi, A., Ghiselli, M., Lutero, E., Osello, R., Riolo, D., Schiaretti, F., Cocchi, M., Leardi, R. IX Colloquium Chemiometricum Mediterraneum, Arles (France)
L'utilizzo della chemiometria per la verifica dell'autenticità di un prodotto alimentare Leardi, R. I Metodi di Controllo – Il Controllo dei Metodi – Dalla Tecnica alla Norma: gli Oli come Sistema Modello – Prima Conferenza Nazionale, Torino
2016
Title Authors Conference
Application of N-Way Methods to Environmental Data from Genoa Leardi, R., Martini, E., Scalabrini, E. 10th Winter Symposium on Chemometrics – WSC-10, Samara (Russia)
Application of rapid Analytical Methods and Multivariate Data Analysis for Evaluating Color, Texture and Flavour Stability of Yogurt Casale, M., Aliakbarian, B., Bagnasco, L., Perego, P., Leardi, R. XVI Chemometrics in Analytical Chemistry, Barcelona
Enhancing spatial resolution of XRF hyperspectral maps via data fusion and PLS regression - when overfitting can be good Oliveri, P., Sciutto, G., Catelli, E., Mazzeo, R., Prati, S., Leardi, R. IASIM, 6th conference in spectral imaging, Chamonix-Mont Blanc
A Multivariate Strategy for the Enhancement of Spatial Resolution in Hyperspectral Maps Oliveri, P., Sciutto, G., Catelli, E., Prati, S., Mazzeo, R., Leardi, R. XXVI Congresso della Divisione di Chimica Analitica della Società Chimica Italiana, Giardini Naxos
Colabilità e caratteristiche microstrutturali delle leghe Cu-Pb-Sn: Indagare l'influenza combinata della composizione e dei parametri sperimentali con un approccio chemiometrico Vernet, J., Piccardo, P., Leardi, R., Montesano, L., Pola, A. 36° Convegno Nazionale Associazione Italiana di Metallurgia, Parma
Chemometrical Strategies in Order to Solve Different Problems in Food Science Casale, M., Oliveri, P., Casolino, M.C., Leardi, R., Lanteri, S. 2nd Imekofoods International Conference, Benevento
Nutrient Deposition in Coastal Waters of the Northwestern Mediterranean Marin, I., Peters, F., Gallisai, R., Aparicio, F.L., Marrasé, C., Leardi, R., Querol, X. XXXII Trobades Cientìfiques de la Mediterrània, Mahon (Spain)
Influence of the Nature of the Irrigation Methods on the Phenomena of Bioaccumulation of Eight Health-Threatening Elements in Rice Grains Spanu, A., Valente, M., Leardi, R., Ciulu, M., Orlandoni, A.M., Barracu, F., Sanna, G. 2nd Imekofoods International Conference, Benevento
2015
Title Authors Conference
Are complex methods always required to solve REAL problems? Leardi, R. 14th Scandinavian Symposium on Chemometrics, Chia Laguna
Multivariate Approach for Micronization of Active Pharmaceutical Ingredient Copelli, D., Falchi, A., Ghiselli, M., Lutero, E., Osello, R., Riolo, D., Schiaretti, F., Cocchi, M., Leardi, R. 14th Scandinavian Symposium on Chemometrics, Chia Laguna
Application of 3-Way Principal Component Analysis for Evaluating Yogurt Stability Casale, M., Bagnasco, L., Aliakbarian, B., Perego, P., Lanteri, S., Leardi, R. XXV Congresso della Divisione di Chimica Analitica, Trieste
2014
Title Authors Conference
FTIR analysis in oil oxidation process Leardi, R., Polotti, G. EuroPACT 2014, Barcelona (Spain)
Is chemometric easy? I think so. For sure it is cheap Leardi, R. ISMEC2014, Pavia
Measurement of trace level dechlorane flame retardants in food and feed by GC-MS/MS Calaprice, C., L'homme, B., Calvano, C.D., Zambonin, C., Leardi, R., Focant, J.F. DIOXIN 2014, Madrid
Characterisation of Ligurian foodstuffs by NIR spectroscopy Bagnasco, L., Simonetti, R., Casale, M., Oliveri, P., Casolino, M.C., Medini, L., Leardi, R., Lanteri, S. Italian Forum on Industrial Biotechnology and Bioeconomy – IFIB 2014, Genoa
Non-selective signals in food analysis Leardi, R., Bagnasco, L., Casale, M., Casolino, M.C., Lanteri, S. 1st IMEKOFOODS, Rome
Micro-Raman imaging for air particulate analysis Simonetti, R., Chöel, M., Lanteri, S., Leardi, R., Duponchel, L. 5th IASIM conference in spectral imaging, Rome
2013
Title Authors Conference
Actuator Performance Comparison by DOE and PCA Copelli, D., Bodria, A., Magnani, I., Militerno, G., Ponticelli, M., Usberti, F., Leardi, R. VIII Colloquium Chemiometricum Mediterraneum, Bevagna
Use of NIR and PLS in Quality Control of Carboxymethylcellulose Leardi, R., Polotti, G., Perelli, S. XXIV Congresso della Divisione di Chimica Analitica della Società Chimica Italiana, Sestri Levante
Prediction of the Optimum Harvest Time of 'Scarlet' Apples using DR-UV–Vis and NIR Spectroscopy Bertone, E., Venturello, A., Leardi, R., Geobaldo, F. BIT's2nd Annual World Congress of Food Science & Technology-2013, Hangzhou (China)
D-Optimal Application as Efficient Tool During Formulation Feasibility Studies of Novel MDIs Drug Products Copelli, D., Brighenti, D., Dagli Alberi, M., Militerno, G., Zambelli, E., Bonelli, S., Schiaretti, L., Schincaglia, M., Leardi, R. Drug Delivery To The Lungs 24, Edinburgh (UK)
2012
Title Authors Conference
Detection of addition of barley to coffee using near infrared spectroscopy and chemometric techniques Ebrahimi-Najafabadi, H., Leardi, R., Oliveri, P., Casolino, C., Jalali-Heravi, M., Lanteri, S. 12th European Symposium on Statistical Methods for the Food Industry, Paris
Multidisciplinar ecosustainable approach for grape marc microwave-mediated extraction of bioactive compounds with potential nutraceutical and cosmeceutical properties Villa, C., Boggia, R., Leardi, R., Zunin, P., Hysenaj, V. CHIMALSI, Ischia
Detection of free fatty acid alkyl esters in olive oils by direct oil thermodesorption and GC-MS analysis Boggia, R., Borgogni, C., Hysenaj, V., Leardi, R., Zunin, P. CHIMALSI, Ischia
Multidisciplinar ecosustainable approach and process intensification in microwave-mediated extractions of bioactive compounds from grape marc Rosa, R., Veronesi, P., Leonelli, C., Caponetti, E., Chillura Martino, D., Boggia, R., Leardi, R., Villa, C. XVIII congresso nazionale della divisionedi chimica industriale della società chimica italiana "Le Sfide della Chimica Industriale per una Innovazione Sostenibile", Florence
2011
Title Authors Conference
Multivariate Analysis in step growth polymerization Leardi, R., Polotti, G. SSC12, Billund (DK)
Prediction of The Half-Wave Potential of Some Benzoxazine Derivatives by Genetic Algorithm and Partial Least Squares Niazi, A., Golami, M., Khosravi, A., Leardi, R. The 14th Asian Chemical Congress, Bangkok (TH)
Detection of fraudulent addition of barley to coffee powder by means of NIR spectroscopy and multivariate regression Ebrahimi-Najafabadi, H., Leardi, R., Oliveri, P., Casolino, C., Jalali-Heravi, M., Lanteri, S. XXIV National Conference of the Italian Society of Chemistry (SCI), Lecce
2010
Title Authors Conference
Genetic Algorithms for wavelength selection in spectral data sets Leardi, R. 11èmes Journées Européennes Agro-Industrie et Méthodes Statistiques, Benevento
Multivariate Analysis applied to industrial production: two case studies Polotti, G., Leardi, R. VII Colloquium Chemiometricum Mediterraneum, Granada (Spain)
Multivariate Analysis applied to industrial production: two case studies Polotti, G., Leardi, R. XII CAC (Chemometrics in Analytical Chemistry), Antwerp (Belgium)
Etude cinétique et chimiométrique multivoie pour l'évaluation de la stabilité thermique d'huiles: comparaison de méthodes Cordella, C., Tekye, T., Rutledge, D.N., Leardi, R. Chimiométrie 2010, Paris
2009
Title Authors Conference
Three-way Principal Component Analysis applied to Noodles Sensory Data Analysis Leardi, R. TRICAP 2009, Nuria (Spain)
2008
Title Authors Conference
Disidratazione del basilico genovese mediante osmosi diretta Boggia, R., Zunin, P., Leardi, R., Evangelisti, F., Lanteri, S. VII Congresso Nazionale di Chimica degli Alimenti, Perugia
Applicazione di metodi statistici multivariati allo studio del pesto genovese Zunin, P., Boggia, R., Evangelisti, F., Salvadeo, P., Lanteri, S., Leardi, R. VII Congresso Nazionale di Chimica degli Alimenti, Perugia
Chemometric study of annual changes and location differences of chemical and physical properties in the Ross Sea surface waters (Antarctica) Massolo, S., Messa, R., Rivaro, P., Leardi, R. CAC 2008, Montpellier
Energy savings using on-line mltivariate distillation monitoring MacNamara, K., Leardi, R., Interwies, U. 3rd Conference Worldwide Distilled Spirits, Edinburgh
2007
Title Authors Conference
Multivariate on-line process monitoring applied to a two-column distillation pilot plant Leardi, R., MacNamara, K. Workshop del Gruppo di Lavoro di Chemometria, Modena
Applications of Experimental Design to Chemical and Food Industry Leardi, R., Paganelli, F., MacNamara, K. Joint ENBIS-DEINDE 2007 Conference, Turin
Optimization of a glucose biosensor setup Mignani, A., Luciano, G., Lanteri, S., Leardi, R., Scavetta, E., Tonelli, D. FKA Tagung Festkoerperanalytik, Vienna
Multivariate on-line process monitoring applied to a continuous two-column distillation pilot plant Leardi, R., MacNamara, C., MacNamara, K. VI Colloquium Chemiometricum Mediterraneum, Saint Maximin La Sainte Baume
Glucose biosensors: study of the optimal setup by experimental design Mignani, A., Luciano, G., Lanteri, S., Leardi, R., Scavetta, E., Tonelli, D. XX Congresso di Chimica Analitica, S. Martino al Cimino
2006
Title Authors Conference
How to convince people that 3-way PCA is useful and easy Leardi, R. TRICAP 2006, Chanià (Greece)
Three-Way PCA as a powerful data display method Leardi, R. 2nd European User Meeting on Multivariate Analysis, Como
Everyday life of a chemometric consultant Leardi, R. 1er Encuentro de Jóvenes Investigadores en Quimiometría, Tarragona
2005
Title Authors Conference
Optimization of a Fast Column Gas Chromatographic method for the analysis of distilled spirits Leardi, R., MacNamara, K., Sabuneti, A. 30 ans de Méthodologie de la Recherche Experimentale, Aix en Provence
A new approach for the monitoring of precursor indicator of dioxin (with special FTIR technology) Bravi, R., Leardi, R. 10th EuCheMS-DCE International Conference on Chemistry and the Environment, Rimini
Les Algorithmes Génétiques pour la sélection de régions spectrales Leardi, R. Quatrièmes Rencontres Hélio-SPIR, Montpellier
2004
Title Authors Conference
Genetic Algorithms as an automated Variable Selection method for chemometric models Leardi, R. 8th NIR Nord Midwinter Meeting, Umeå
Genetic Algorithms in Variable Selection Leardi, R. 16. Norske kjemometrisymposium, Geilo (Norway)
Coupling of Fast Wavelet Transform and Genetic Algorithms for efficient variable selection in multivariate calibration tasks Cocchi, M., Leardi, R., Ulrici, A. CAC, 9th International Conference, Lisbon
2003
Title Authors Conference
Genetic-algorithm-based wavelength selection in multicomponent spectrophotometric determination by PLS: application on copper and zinc mixture Ghasemi, J., Niazi, A., Leardi, R. 12th Iranian Seminar of Analytical Chemistry, Babolsar
Selection of the NIRS regions predictive of fatty acid and erucic acid contents in Brassica juncea seeds by interval-PLS and genetic algorithm-PLS Leardi, R., Armanino, C., Font Villa, R., De Haro Bailón, A. Colloquium Chemiometricum Mediterraneum V, Ustica
Sequential application of backward interval-PLS and Genetic Algorithms for wavelength selection Leardi, R., Nørgaard, L. Colloquium Chemiometricum Mediterraneum V, Ustica
Application of 3-way Principal Component Analysis to water quality assessment of the Venice lagoon Leardi, R., Tercier-Waeber, M.L., Gianni, B., Ferrari, G. Colloquium Chemiometricum Mediterraneum V, Ustica
Use of 3-Way PCA as data display method Leardi, R. Chimiométrie 2003, Paris
2002
Title Authors Conference
Sensory quality of strawberry cultivars Leardi, R., Patz, C., Schöpplein, E. 3rd International Chemometrics Research Meeting, Veldhoven
Selection of the NIRS regions predictive of oil and erucic acid contents in samples of Brassica juncea by Genetic Algorithm-PLS Leardi, R., Armanino, C., Font Villa, R., de Haro Bailón, A. XVII Congresso Nazionale di Chimica Analitica, Viareggio
Maximizing Macromolecule Crystal Size for Neutron Diffraction Experiments Judge, R., Kephart, R., Leardi, R., Myles, D.A., Snell, E.H., vanderWoerd, M. XIX Congress and General Assembly of the International Union of Crystallography, Geneva
Genetic Algorithms for Wavelength Selection in Spectral Data Sets Leardi, R. Kemometria '02, Tata
2001
Title Authors Conference
Experiences with genetic algorithms for feature selection Yoshida, H., Leardi, R., Funatsu, K., Varmuza, K. 15. CIC Workshop der Fachgruppe Chemie-Information-Computer der Gesellschaft Deutscher Chemiker, Leipzig
Schnelle Fruchtsaft-Analytik mittels FT-Infrarot-Spektroskopie am Beispiel von Apfelsäften Blieke, A., Patz, C.D., Giehl, A., Dietrich, H., Leardi, R., Büning-Pfaue, H. Intervitis/Interfructa, Stuttgart
Genetic algorithms for feature selection in mass spectra classification Yoshida, H., Leardi, R., Funatsu, K., Varmuza, K. Int. Congress on Analytical Sciences 2001 (ICAS 2001), Tokyo
Application of Genetic Algorithm-PLS to the determination of wine parameters from FTIR spectra Leardi, R., Patz, C.D., Blieke, A. SSC7, 7th Scandinavian Symposium on Chemometrics, Copenhagen
3-Way Principal Component Analysis delle concentrazioni di specie inorganiche in campioni di acqua e sedimento prelevati nel fiume Tronto Armanino, C., Leardi, R., Locatelli, C., Torsi, G. XVI Congresso Nazionale di Chimica Analitica, Portonovo
Automated Variable Selection for Multivariate Calibration Leardi, R., Seasholtz, M.B., Pell, R.J. Federation of Analytical Chemistry and Spectroscopy Societies (FACSS), Detroit
2000
Title Authors Conference
Feature selection by Genetic Algorithms for mass spectral classifiers Yoshida, H., Leardi, R., Funatsu, K., Varmuza, K. CAC-2000, Seventh International Conference on Chemometrics in Analytical Chemistry, Antwerp
1999
Title Authors Conference
Studio chemiometrico sull'inquinamento da metalli nel suolo di uno stabilimento industriale Crisponi, G., Cristiani, F., Nurchi, V.M., Verani, G., Leardi, R. Conferenza Organizzativa "Inquinamento del Suolo da Metalli Pesanti", Sassari
The application of genetic algorithms for feature selection in spectral data sets Leardi, R. SSC6, 6th Scandinavian Symposium on Chemometrics, Porsgrunn
A chemometric study on the waste water treatment system in a metallurgical plant Crisponi, G., Cristiani, F., Nurchi, V.M., Verani, G., Leardi, R. SSC6, 6th Scandinavian Symposium on Chemometrics, Porsgrunn
Tolfenamic acid gels based on poloxamer 407. Evaluation by a mixture experimental design Cafaggi, S., Leardi, R., Parodi, B., Caviglioli, G., Bignardi, G. Drug delivery for the third millennium, Pisa
1998
Title Authors Conference
Three-way PCA applied to environmental and food chemistry: some examples Leardi, R. 2nd International Chemometrics Research Meeting, Veldhoven
Direct injection of distilled spirits with PTV Matrix Removal: the perfect splitless injection? MacNamara, K., Leardi, R., Hoffmann, A. 20th International Symposium on Capillary Chromatography, Riva del Garda
Empirical Modelling of interferences in Graphite Furnace Atomic Absoption Spectroscopy Grotti, M., Tiseo, A., Magi, E., Leardi, R. 3rd European Furnace Symposium, Prague
1997
Title Authors Conference
Applicazione di tecniche di analisi statistica multivariata in campo ambientale marino Leardi, R., Grotti, M., Rivaro, P., Soggia, F., Frache, R. La contaminazione da microinquinanti, Venice
3-Way PCA as a powerful display method in environmental and food problems Leardi, R., Armanino, C. TRICAP '97, Manson (USA)
Chemometrics: a brief review of the statistical tools for food authentication Leardi, R. European Symposium "Food authenticity", La Baule
1996
Title Authors Conference
Analisi dei dati provenienti dal monitoraggio chimico analitico delle acque della laguna veneta: dalla Analisi dei Componenti Principali alla 3-way PCA Armanino, C., Leardi, R., Lanteri, S., Forina, M., Alberotanza, L. Progetto "Sistema Lagunare Veneziano", Venice
3-way PCA in water characterization by chemical measurements. A study on the Venice Lagoon Leardi, R., Armanino, C., Alberotanza, L. CAC '96, Tarragona
Genetic Algorithms as a tool for feature selection and its application in NIR Leardi, R. 8th International Diffuse Reflectance Conference, Chambersburg (USA)
3-way PCA and its applications in environmental and food chemistry Leardi, R., Armanino, C. Euroanalysis IX, Bologna
Application of 3-way PCA to environmental and food chemistry Leardi, R. Unscrambler User's Club Meeting, Copenhagen
1995
Title Authors Conference
Genetic Algorithms in Feature Selection Leardi, R. SAS - 3rd Symposium on Analytical Sciences, Paris
Genetic Algorithms in feature selection Leardi, R. Second International Workshop on Neural Networks and Genetic Algorithms Applied to QSAR and Drug Design, Lyon
Development and set-up of drug electroanalysis by experimental design Pinzauti, S., Gratteri, P., Furlanetto, S., Leardi, R., La Porta, E. VI convegno su Recenti Sviluppi e Applicazioni nell'Analisi Farmaceutica, Milan
Studio dei meccanismi di atomizzazione, in presenza o meno di modificatori di matrice, nella determinazione ETA-AAS di tellurio in campioni ambientali Grotti, M., Contegno, F., Leardi, R. XII Congresso Nazionale di Chimica Analitica "Il ruolo della Chimica Analitica per la Salute e l'Ambiente", Florence
Applicazione di metodi chemiometrici alla ricerca dello standard interno ottimale per la determinazione di metalli pesanti nei sedimenti, mediante ICP-AES Grotti, M., Pantani, R., Leardi, R. XII Congresso Nazionale di Chimica Analitica "Il ruolo della Chimica Analitica per la Salute e l'Ambiente", Florence
1994
Title Authors Conference
Definizione di intervalli di fiducia per le tecniche di classificazione e di regressione multivariate. Selezione delle variabili mediante algoritmi genetici Forina, M., Lanteri, S., Armanino, C., Leardi, R., Drava, G., Boggia, R. Secondo Convegno Nazionale di Informatica Chimica, Casalecchio di Reno
Study on the effects of supplemental dietary fat on milkfat composition: a chemometrical approach Leardi, R., Contarini, G. Colloquium Chemiometricum Mediterraneum, Bastia
Application of chemometrics to the production of disc brake pads: analysis of previous data and search of new formulations Leardi, R., Drava, G., Portesani, A., Sales, E. Colloquium Chemiometricum Mediterraneum, Bastia
Genetic algorithms applied to feature selection: from the original algorithm to a hybrid algorithm Leardi, R. Colloquium Chemiometricum Mediterraneum, Bastia
Genetic Algorithms for variable selection Leardi, R. Nordic Workshop in Chemometrics, STUMLAD, Reykjavik
Supplemental fat for dairy cows: effects on milk composition Toppino, P.M., Leardi, R., Dell'Orto, V., Bontempo, V., Mainetti, F. XXIV International Dairy Congress. Brief communications, Melbourne
Design and variable optimization in the adsorptive stripping voltammetric determination of rufloxacin in tablets, human plasma and urine Pinzauti, S., Furlanetto, S., Gratteri, P., Leardi, R. 5th International Symposium on Pharmaceutical and Biomedical Analysis, Stockholm
1993
Title Authors Conference
Genetic Algorithms and their application in chemometrics Leardi, R. Deauville Conference - Symposium on Analytical Chemistry, Deauville
Use of experimental design to optimize the performances of the volatiles compound extraction by using dynamic headspace techniques followed by TCT/GC Contarini, G., Leardi, R. 15th International Symposium on Capillary Chromatography, Riva del Garda
NOx reduction by oil reburning. Application of some correlation techniques to parametrize the process Ghiribelli, L., Pasini, S., Cioni, M., Schiavetti, M., Leardi, R., Lanteri, S. The Combustion Institute, Joint Meeting of the Italian and Spanish Sections, Stresa
Genetic algorithms in feature selection, outlier detection
1992
Title Authors Conference
Prevalence of different viral infections in IVDA Masino, M., Carubia, F., Cartasegna, A., Massacane, R., Leardi, R. XXX Convegno Nazionale di Studi SIITS-AICT, Rome
La calibrazione in NIRS: procedimenti di calcolo e di convalida della funzione di calibrazione Forina, M., Drava, G., Armanino, C., Boggia, R., Lanteri, S., Leardi, R., Corti, P., Conti, P., Giangiacomo, R., Galliena, C., Bigoni, R., Quartari, I., Serra, C., Ferri, D., Leoni, O., Lazzeri, L. Convegno Nazionale di Chimica Analitica, Pavia
Il trasferimento della equazione di calibrazione tra differenti strumenti in NIRS Forina, M., Drava, G., Armanino, C., Boggia, R., Lanteri, S., Leardi, R., Corti, P., Conti, P., Giangiacomo, R., Galliena, C., Bigoni, R., Quartari, I., Serra, C., Ferri, D., Leoni, O., Lazzeri, L. Convegno Nazionale di Chimica Analitica, Pavia
Possibilità di una nuova classificazione per le acque minerali italiane Franco, M.A., Sferlazzo, G., Puggioni, V.R., Leardi, R., Piana, A., Azara, A. XV Congresso di Merceologia, Rome
Application of experimental design techniques to process optimization Cioni, M., Traniello Gradassi, A., Malloggi, S., Schiavetti, M., Nannini, S., Leardi, R. The Combustion Institute Joint Meeting of French, Italian and Swedish Sections, Capri
Associazione tra anticorpi anti N-14 ed altri test per l'epatite C Masino, M., Massacane, R., Carubia, F., Cartasegna, A., Leardi, R. 3rd Meeting "Giornate Internazionali di Aggiornamento sull'Epatite Virale", Genoa
1991
Title Authors Conference
Dairy goats nutrition: chemometric evaluation of the effects of liquid feed and protected fat on milk composition Contarini, G., Leardi, R., Drava, G., Zucchetti, S., Corino, C. III Congreso Mundial de Tecnología de Alimentos, Barcelona
Regressione non-lineare con algoritmo ACE: Variante estrapolativa e convalida completa nell'accoppiamento con il metodo dei minimi quadrati parziali (PLS) Forina, M., Armanino, C., Lanteri, S., Leardi, R., Drava, G. 1° Convegno Nazionale di Informatica Chimica, Venice
Chemometrical techniques in food characterization Leardi, R., Drava, G., Lanteri, S. 2èmes journées "Agro-Industrie et Methodes Statistiques", Nantes
Algoritmi genetici e applicazioni in problemi di ottimizzazione Leardi, R., Boggia, R., Terrile, M. X Congresso Nazionale della Divisione di Chimica Analitica, Turin
Genetic algorithms and their application in optimization Leardi, R., Boggia, R., Terrile, M. Colloquium Chemiometricum Mediterraneum, S. Miniato
Fluidodynamic and thermal characterization of a 50 kW experimental furnace - Experimental Design Malloggi, S., Schiavetti, M., Drava, G., Leardi, R. Colloquium Chemiometricum Mediterraneum, S. Miniato
A chemometric study of chemical composition of mineral waters Tomas, X., Molins, J.J., Garcia-Espeso, V., Leardi, R., Sferlazzo, G.V. Colloquium Chemiometricum Mediterraneum, S. Miniato
1990
Title Authors Conference
Multivariate data analysis in wines and musts - Classification according to vintage year Dalla Serra, A., Leardi, R., Seeber, R., Sferlazzo, G., Versini, G. Euroanalysis VII, Vienna
Tecniche di analisi multivariata nella caratterizzazione di prodotti alimentari Del Caro, A., Franco, M.A., Leardi, R., Seeber, R., Sferlazzo, G., Versini, G. I Congresso Nazionale di Chimica degli Alimenti, Messina and Giardini Naxos
Applicazione della chemiometria alla chimica analitica industriale e di processo Leardi, R., Moizo, E., Cioni, M., Schiavetti, M. IX Congresso Nazionale - Divisione di Chimica Analitica, Ferrara
1989
Title Authors Conference
Flue gas desulfurisation by Ca(OH)2 injection. Application to a 35 MWe tangential oil fired boiler Cioni, M., Gualerci, M., Pardini, G.P., Pedrelli, G., Leardi, R. Joint Meeting of the German and Italian sections of the Combustion Institute, Ravello
L'estensione del package PARVUS: metodi di clustering, modellamento, correlazione Forina, M., Leardi, R., Armanino, C., Lanteri, S. Convegno Nazionale di Chemiometria, Venice
Metodologie di disegno sperimentale applicate alla sperimentazione di processi Leardi, R., Cioni, M., Schiavetti, M. Convegno Nazionale di Chemiometria, Venice
1988
Title Authors Conference
Chemometrical analysis of tuscan oils by PARVUS and AUTOCAD as a display output Lanteri, S., Armanino, C., Leardi, R., Forina, M. Euchem Conference on Chemometrics in Organic and Bioorganic Chemistry, Trieste
Tecniche di modellamento multivariate e relativi programmi per computers in BASIC MS-DOS Forina, M., Armanino, C., Lanteri, S., Leardi, R. Bononiachem '88, XVI congresso nazionale di chimica, Bologna
1987
Title Authors Conference
Metodi di rotazione Varimax Forina, M., Lanteri, S., Leardi, R. Colloquium Chemiometricum Mediterraneum, Barcelona
Feature Selection by stepwise Bayesian Analysis Lanteri, S., Leardi, R., Forina, M. Colloquium Chemiometricum Mediterraneum, Barcelona
1986
Title Authors Conference
The number of principal components Forina, M., Lanteri, S., Leardi, R. III CAC, Lerici
Feature Selection by Stepwise Bayesian Analysis Forina, M., Lanteri, S., Leardi, R. COBAC IV, Graz
1985
Title Authors Conference
Scelta delle variabili rilevanti mediante classificazione bayesiana progressiva Forina, M., Lanteri, S., Castino, M., Leardi, R. VI Congresso Nazionale - Divisione di Chimica Analitica, Bari

Books & Book Chapters

Our contributions to educational and reference materials

World Scientific Publishing • 2025

Basic Chemometrics for Analytical Chemists

Comprehensive textbook combining theoretical foundations with practical CAT software training.

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Year Title Authors Publication
2025 Chapter 4 - Statistical Experimental Design Leardi, R.; Farinini, E. Book chapter in "Basic Chemometrics for Analytical Chemists", World Scientific Publishing
2018 D-Optimal designs Leardi, R. Encyclopedia of Analytical Chemistry
2017 Data Handling Leardi, R. In "Advances in Food Diagnostics, Second Edition", F. Toldrà and L. Nollet eds., Wiley - Blackwell
2013 Experimental Design Leardi, R. In "Chemometrics in Food Chemistry", F. Marini ed., in Data Handling in Science and Technology series, vol. 28, Chennai, Elsevier
2013 Methods of Treatment of Data Leardi, R. In "Handbook of Water Analysis, third edition", L. Nollet and L.S.P. De Gelder, eds., Taylor and Francis Group, LLC
2009 Genetic algorithms in Chemistry Leardi, R. In "Comprehensive Chemometrics: Chemical and Biochemical Data Analysis", S. Brown, R. Tauler and B. Walczak eds., Elsevier, Oxford, vol. 1
2008 Chemometric methods in food authentication Leardi, R. In "Modern Techniques for Food Authentication", Da-Wen Sun ed., Elsevier
2007 Methods of Treatment of Data Leardi, R. In "Handbook of Water Analysis, second edition", L. Nollet ed., Taylor and Francis Group, LLC
2007 Data Processing Leardi, R. In "Advances in Food Diagnostics", L. Nollet and F. Toldrà eds., Ames, ISUP - Blackwell Publishing
2006 Chemometrics in Data Analysis Leardi, R. In "Chromatographic Analysis of the Environment: Third Edition, Revised and Expanded", L. Nollet ed., in Chromatographic Science Series, vol. 93, Boca Raton, CRC Press Taylor and Francis

Research Impact

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150+
Scientific Publications
150+
Conference Presentations
10+
Books & Chapters
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Years of Experience

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